A biomarker is a substance or a change that can be measured in tissue, blood, or other bodily fluids, and that may signal an abnormal bodily process and/or disease. In cancer, biomarkers may be specific genetic abnormalities that may be identified as the “driver” that is causing the cancer to grow and spread. “Molecular marker,” or “genotype,” are other terms that may be used to describe biomarkers.1,2